The present study is to expose the bio-accumulation of heavy metals in vital organs of the fresh water fish, M.keletius reared in heavy metal contaminated medium. The experimental fish assayed to Ni, Cd, Cr and Pb at sub lethal concentrations for 28 days. The metals, Ni, Cd, Cr and Pb assayed using Atomic absorption spectrophotometry and the results given as ug/g dry weight. The liver tissue shown high accumulation during the exposure period. All results are statistically significant at p<0.05. The order of heavy metal accumulation in liver and gill tissues was Cd>Pb>Cr>Ni and Pb>Cd>Cr>Ni . The bioaccumulation of cadmium and lead proportion was much increased in the tissues of Mystus keletius.
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